x1 = The_FOD_in_the_circulation__X1 x2 = The_FOD_in_the_metabolizing_tissues__X4 x3 = The_cumulative_FOD_excreted_in_the_non_urinary_pool__X3 x4 = The_FOD_in_the_gallbladder___intestinal_lumen__X5 x5 = The_cumulative_FOD_excreted_in_the_urine__X2