Ligand_EGF + Surface_Receptor_External -> Receptor_Ligand_Complex Receptor_Ligand_Complex -> Surface_Receptor_External Free_pit_proteins + Receptor_Ligand_Complex -> Receptor_Ligand_Pit_Protein_complex Receptor_Ligand_Pit_Protein_complex -> Receptor_Ligand_Complex Surface_Receptor_External -> Internalised_receptors Receptor_Ligand_Complex -> Internalised_Ligand + Internalised_receptors Receptor_Ligand_Pit_Protein_complex -> Internalised_Ligand + Internalised_receptors Internalised_Ligand -> 0 Internalised_receptors -> Surface_Receptor_External